Gene Editing Is Now Precise Enough to Modify a Single Letter of DNA


Gene editing has the power to completely reshape our world. It promises everything from fixing the genetic faults that lead to disease, to destroying disease-causing microbes, to improving the nutrition of the foods we eat and even resurrecting extinct species like the wooly mammoth—all largely thanks to the genetic editing tool CRISPR, which has both popularized this work and made it possible. Now, researchers in Japan have developed a new gene editing technique that uses CRISPR alongside a DNA repair system to modify a single DNA base in the human genome, with what the team’s press release calls “absolute precision.”

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